The microbiome has been associated with the development of cancer. Here, we demonstrate that pks+ E.Coli directly induces DNA mutations in organoids. In a large cancer dataset, we discover that this process is active during the onset of colorectal cancer.
Immunology, cancer etiology, immunotherapy, genomics
About me
Understanding cancer mechanisms and devising strategies to either target these aberrant cells or even prevent them from developing especially motivates me to do research. I have a strong background in (tumor) immunology and now work on childhood leukemia and lymphoma.
Seino Jongkees
Country
Company
Utrecht University
Job title
PI
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Julia Bauzá-Martinez
Country
Company
UU, Faculty of Science
Job title
PhD student
Interests
mass spectrometry, peptidomics, plants, climbing
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Andreas Sonnen
Country
Company
UMC Utrecht
Job title
Assistant Professor
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Anton Venhuizen
Country
Company
UMC Utrecht
Job title
PhD student
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Karla De la O Becerra
Country
Company
Utrecht University
Job title
PhD candidate
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Hugo Ingen
Country
Company
UU, Faculty of Science
Job title
Assistant Professor
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Anneloes Keijzer
Country
Company
UMC Utrecht
Job title
Master student
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Hans de Cock
Country
Company
UU, Faculty of Science
Job title
Assistant Professor
Interests
Fungal infections in humans and animals
About me
Hans de Cock studied biology (B4, chemical biology) at Utrecht University (UU) (1980-1986). He performed his graduate research in Molecular Microbiology at UU and received his Ph.D. in 1991 with his thesis entitled: "Biogenesis of outer membrane protein PhoE of Escherichia coli K-12: studies on protein conformation” He worked as NWO postdoctoral fellow in the Biochemistry and Biophysics laboratory with Prof. dr. Linda Randall at Washington State University in Pullman, USA on protein folding. In 1992, he became Fellow of the Royal Academy of Arts and Sciences of the Netherlands and assistant professor at Molecular Microbiology at the UU and worked till 2003 on bacterial protein and lipid transport and subsequently on fungal infection due to Cryptococcus and since 2010 due to Aspergillus
Olga Jarosinska
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Company
Utrecht University
Job title
Master's Student
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Soufian el Makrini
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Company
UMC Utrecht
Job title
PhD student
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Merlin Lederer
Country
Company
UU, Faculty of Science
Job title
Bachelor student
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Danny Wilbie
Country
Company
Utrecht University
Job title
PhD Candidate
Interests
Protein delivery, CRISPR, gene therapy
About me
I am a second year PhD candidate in the Department of Pharmaceutics at UU university, in the group of Enrico Mastrobattista. My research focusses on the feasibility of applying CRISPR/Cas gene editing for gene correction in vivo.
Jesko Wagner
Country
Company
Utrecht University
Job title
Master Student
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Jan Huertas
Country
Company
Hubrecht Institute
Job title
PhD Student
Interests
About me
Born in Barcelona.
I studied Human Biology at the Pompeu Fabra University, in Barcelona, where I also cursed my masters in Bioinformatics.
Currently I'm at the Max Planck Institute for Biomedicine, in Münster, Germany, finishing my PhD under the supervision of Vlad Cojocaru (Hubrecht Institute)
Bart Gadella
Country
Company
Utrecht University
Job title
Associate professor
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Karen Anker
Country
Company
Hubrecht Institute
Job title
Bachelor student
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Maik Derks
Country
Company
UU
Job title
Faculty of Science - PhD
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Sem Tamara
Country
Company
Utrecht University
Job title
Postdoc
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Iris Bally-2
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Company
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Interests
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